4-Acetylantroquinonol B induced DNA damage response signaling and apoptosis via suppressing CDK2/CDK4 expression in triple negative breast cancer cells

Author:

Satriyo Pamungkas Bagus,Su Chih Ming,Ong Jiann Ruey,Huang Wen-Chien,Fong Iat-Hang,Lin Chih-Cheng,Aryandono Teguh,Haryana Sofia Mubarika,Deng Li,Huang Chun-Chih,Tzeng Yew-Min,Chao Tsu-Yi,Liu Hui-Wen,Yeh Chi-Tai

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference25 articles.

1. Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence;Balko;Sci. Transl. Med.,2016

2. 4-acetyl-antroquinonol B suppresses SOD2-enhanced cancer stem cell-like phenotypes and chemoresistance of colorectal cancer cells by inducing hsa-miR-324 re-expression;Bamodu;Cancers (Basel),2018

3. Inhibition of dna repair mechanisms and induction of apoptosis in triple negative breast cancer cells expressing the human herpesvirus 6 u94;Caccuri;Cancers (Basel).,2019

4. Overall Cdk activity modulates the DNA damage response in mammalian cells;Cerqueira;J. Cell Biol.,2009

5. 4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype;Chang;Toxicol. Appl. Pharmacol.,2015

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