Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure–activity relationships

Author:

Bai Jie,Zhao Shengyu,Fan Xiaoqing,Chen Yonghui,Zou Xiaowen,Hu Minwan,Wang Baolian,Jin Jing,Wang Xiaojian,Hu Jinping,Zhang Dan,Li Yan

Funder

State Key Laboratory of Bioactive Substance and Function of Natural Medicines

Institute of Materia Medica

Chinese Academy of Medical Sciences

Peking Union Medical College

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference52 articles.

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3. Biochemical, cellular, and pharmacological aspects of the multidrug transporter;Ambudkar;Annu. Rev. Pharmacol. Toxicol.,1999

4. The inhibitory effects of nobiletin on P-glycoprotein and the study of molecular mechanism;Bai;Acta Pharm. Sin.,2018

5. P-gp inhibition potential in cell-based models: which “calculation” method is the most accurate?;Balimane;AAPS J.,2008

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