The combination of multiple doses of etanidazole and pimonidazole in 48 patients: a toxicity and pharmacokinetic study
Author:
Publisher
Elsevier BV
Subject
Radiology, Nuclear Medicine and imaging,Oncology,Hematology
Reference10 articles.
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2. Relationship between the neurotoxicity of the hypoxic cell radiosensitiser SR 2508 and pharmacokinetic profile;Coleman;Cancer Res.,1987
3. Additivity of radio-sensitization by the combination of SR 2508 (etanidazole) and Ro 03-8799 (pimonidazole) in a murine tumour system;Honess;Int. J. Radiat. Oncol. Biol. Phys.,1988
4. A phase I study of the combination of two hypoxic cell radiosensitisers Ro 03-8799 and SR 2508: toxicity and pharmacokinetics;Newman;Int. J. Radiat. Oncol. Biol. Phys.,1986
5. The multi-dose clinical tolerance and pharmacokinetics of the combined radiosensitisers, Ro 03-8799 (pimonidazole) and SR 2508 (etanidazole);Newman;Int. J. Radiat. Oncol. Biol. Phys.,1988
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3. Bioreductively-activated prodrugs for targeting hypoxic tissues: Elimination of aspirin from 2-nitroimidazole derivatives;Bioorganic & Medicinal Chemistry Letters;1999-05
4. Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells;British Journal of Cancer;1997-07
5. Mechanism of the selective hypoxic cytotoxicity of 1-methyl-2-nitroimidazole;Biochemical Pharmacology;1994-07
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