Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila
Author:
Funder
University Grants Commission
Publisher
Elsevier BV
Subject
Developmental Neuroscience,Neurology
Reference59 articles.
1. Posttranslational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity;Arbez;J. Biol. Chem.,2017
2. Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity;Atwal;Hum. Mol. Genet.,2007
3. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders;Ballatore;Nat. Rev. Neurosci.,2007
4. Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease;Barbaro;Hum. Mol. Genet.,2015
5. An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases;Bischof;Proc. Natl. Acad. Sci.,2007
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1. Differential Effects of Post-translational Modifications on the Membrane Interaction of Huntingtin Protein;ACS Chemical Neuroscience;2024-05-16
2. Differential Effects of Posttranslational Modifications on the Membrane Interaction of Huntingtin Protein;2023-12-01
3. IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway;Life Science Alliance;2023-08-08
4. Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies;Frontiers in Neuroscience;2023-05-18
5. Mutation of S461, in the GOLGA3 phosphorylation site, does not affect mouse spermatogenesis;PeerJ;2023-04-17
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