Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease-Reference-Cited by-同舟云学术

Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease

Published:2014-10-09 Issue:4 Volume:24 Page:913-925
ISSN:1460-2083
Container-title:Human Molecular Genetics
language:en
Short-container-title:

Author:

Barbaro Brett A.,Lukacsovich Tamas,Agrawal Namita,Burke John,Bornemann Doug J.,Purcell Judith M.,Worthge Shane A.,Caricasole Andrea,Weiss Andreas,Song Wan,Morozova Olga A.,Colby David W.,Marsh J. Lawrence

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

Link

http://academic.oup.com/hmg/article-pdf/24/4/913/14143563/ddu504.pdf

Reference50 articles.

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3. N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease;Ratovitski;Cell Cycle,2007

4. Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells;Wellington;J. Biol. Chem.,2000

5. Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches;Wellington;Clin. Genetics,2000

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