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How to improve research on management of critically ill patients: Lessons learned from negative randomised clinical trials in the intensive care unit

  • Published:2020-04 Issue:2 Volume:39 Page:173-174
  • ISSN:2352-5568
  • Container-title:Anaesthesia Critical Care & Pain Medicine
  • language:en
  • Short-container-title:Anaesthesia Critical Care & Pain Medicine

Author:

Rello Jordi,Blanch Lluis,Preiser Jean-Charles,De Waele Jan J.

Funder

Research Foundation Flanders

Publisher

Elsevier BV

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine,General Medicine

Reference15 articles.

1. Evidence supporting recommendations from international guidelines on treatment, diagnosis and prevention of HAP and VAP;Campogiani;EJCMID,2019

2. Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults;Rello;Clin Microbiol Infect,2017

3. Early goal-directed therapy in the treatment of severe sepsis and septic shock;Rivers;N Engl J Med,2001

4. Towards precision medicine in sepsis;Rello;Clin Microbiol Infect,2018

5. Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs. low PEEP on mortality in patients with acute respiratory distress syndrome: a randomized clinical trial;Writing group for the alveolar recruitment for acute respiratory distress syndrome trial (ART) et al.;JAMA,2017

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