SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA-Reference-Cited by-同舟云学术

SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA

Published:2024-03 Issue:3 Volume:5 Page:101439
ISSN:2666-3791
Container-title:Cell Reports Medicine
language:en
Short-container-title:Cell Reports Medicine

Author:

Germani Serena,Van Ho Andrew Tri,Cherubini Alessandro,Varone Ersilia,Chernorudskiy Alexander,Renna Giorgia Maria,Fumagalli Stefano,Gobbi Marco,Lucchetti Jacopo,Bolis Marco,Guarrera Luca,Craparotta Ilaria,Rastelli Giorgia,Piccoli Giorgia,de Napoli Cosimo,Nogara Leonardo,Poggio Elena,Brini Marisa,Cattaneo Angela,Bachi Angela,Simmen Thomas,Calì Tito,Quijano-Roy Susana,Boncompagni Simona,Blaauw Bert,Ferreiro Ana,Zito Ester^ORCID

Funder

Ministero della Salute

Ministero dell'Istruzione dell'Università e della Ricerca

Publisher

Elsevier BV

Reference56 articles.

1. Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity;Chernorudskiy;Proc. Natl. Acad. Sci. USA,2020

2. SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyper-oxidation by means of redox-regulating SERCA2 pump activity;Marino;Hum. Mol. Genet.,2015

3. A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss;Pozzer;Redox Biol.,2019

4. Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy;Filipe;Cell Death Differ.,2021

5. Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses;Rizzuto;Science,1998

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