Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk
Author:
Funder
Wellcome Trust
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference63 articles.
1. Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart;Bottino;Prog. Biophys. Mol. Biol.,2006
2. An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment;Davies;Am. J. Physiol. Heart Circ. Physiol.,2012
3. Prediction of Thorough QT study results using action potential simulations based on ion channel screens;Mirams;J. Pharmacol. Toxicol. Methods,2014
4. Comprehensive in vitro Proarrhythmia Assay, a novel in vitro/in silico paradigm to detect ventricular proarrhythmic liability: a visionary 21st century initiative;Cavero;Expert Opin. Drug Saf.,2014
5. MICE models: superior to the HERG model in predicting Torsade de Pointes;Kramer;Sci. Rep.,2013
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