Prediction of Thorough QT study results using action potential simulations based on ion channel screens
Author:
Funder
EPSRC
Microsoft Research
NC3Rs/EPSRC
Wellcome Trust
Royal Society
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference38 articles.
1. Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge;Beattie;Journal of Pharmacological and Toxicological Methods,2013
2. Multiscale modelling of drug-induced effects on cardiac electrophysiological activity;Brennan;European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences,2009
3. In vitro and in vivo models for testing arrhythmogenesis in drugs;Carlsson;Journal of Internal Medicine,2006
4. Considerations for the use of cellular electrophysiology models within cardiac tissue simulations;Cooper;Progress in Biophysics and Molecular Biology,2011
5. High-throughput functional curation of cellular electrophysiology models;Cooper;Progress in Biophysics and Molecular Biology,2011
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