Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge-Reference-Cited by-同舟云学术

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Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge

Published:2013-07 Issue:1 Volume:68 Page:88-96
ISSN:1056-8719
Container-title:Journal of Pharmacological and Toxicological Methods
language:en
Short-container-title:Journal of Pharmacological and Toxicological Methods

Author:

Beattie Kylie A.,Luscombe Chris,Williams Geoff,Munoz-Muriedas Jordi,Gavaghan David J.,Cui Yi,Mirams Gary R.

Funder

National Centre for the Replacement Refinement and Reduction of Animals in Research

Engineering and Physical Sciences Research Council

GlaxoSmithKline

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference44 articles.

1. PETSc users manual revision 3.3;Balay,2012

2. Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function;Bishop;American Journal of Physiology. Heart and Circulatory Physiology,2010

3. Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart;Bottino;Progress in Biophysics and Molecular Biology,2006

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