Targeting Obesity and Cachexia: Identification of the GFRAL Receptor–MIC-1/GDF15 Pathway
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Molecular Medicine
Reference12 articles.
1. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand;Yang;Nat. Med.,2017
2. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates;Mullican;Nat. Med.,2017
3. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL;Emmerson;Nat. Med.,2017
4. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15;Hsu;Nature,2017
5. Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum;Welsh;Proc. Natl. Acad. Sci. U. S. A.,2003
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