Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Immunology
Reference77 articles.
1. Standard conformations for the canonical structures of immunoglobulins;Al-Lazikani;J. Mol. Biol.,1997
2. Antigen-independent selection of intracellular stable antibody frameworks;Auf der Maur;Methods,2004
3. The Protein Data Bank;Berman;Nucleic Acids Res.,2000
4. Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria;Biocca;Biotechnology (NY),1995
5. Single-chain antigen-binding proteins;Bird;Science,1988
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Humanization and characterization of an anti-ciguatoxin CTX3C monoclonal antibody;Toxicon;2024-08
2. For antibody sequence generative modeling, mixture models may be all you need;Bioinformatics;2024-04-23
3. Development and in vitro characterization of a humanized scFv against fungal infections;PLOS ONE;2022-10-31
4. Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3;Protein Science;2022-10-26
5. Pilot study of a novel nanobody 68 Ga-NODAGA-SNA006 for instant PET imaging of CD8+ T cells;European Journal of Nuclear Medicine and Molecular Imaging;2022-07-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3