Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3-Reference-Cited by-同舟云学术

Molecular basis for thermal stability and affinity in a VHH: Contribution of the framework region and its influence in the conformation of the CDR3

Author:

Kinoshita Seisho¹^ORCID,Nakakido Makoto¹²^ORCID,Mori Chinatsu²,Kuroda Daisuke¹²³,Caaveiro Jose M.M.⁴^ORCID,Tsumoto Kouhei¹²⁵

Affiliation:

1. Department of Bioengineering, School of Engineering The University of Tokyo Tokyo Japan

2. Department of Chemistry and Biotechnology, School of Engineering The University of Tokyo Tokyo Japan

3. Research Center for Drug and Vaccine Development National Institute of Infectious Diseases Tokyo Japan

4. Laboratory of Global Healthcare, Graduate School of Pharmaceutical Sciences Kyushu University Fukuoka Japan

5. Medical Proteomics Laboratory, The Institute of Medical Science The University of Tokyo Tokyo Japan

Funder

Japan Agency for Medical Research and Development

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Link

Reference51 articles.

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