Local secretion/shedding of tumor-derived CD83 molecules as a novel tumor escape mechanism
Author:
Publisher
Elsevier BV
Subject
Molecular Biology,Immunology
Reference7 articles.
1. Expression of a dendritic cell maturation marker CD83 on tumor cells from lung cancer patients and several human tumor cell lines––is there a biological meaning behind it?;Baleeiro;Cancer Immunol. Immunother.,2008
2. CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells;Cao;Biochem. J.,2005
3. Engagement of CD83 ligand induces prolonged expansion of CD8+ T cells and preferential enrichment for antigen specificity;Hirano;Blood,2006
4. The soluble form of CD83 is present at elevated levels in a number of hematological malignancies;Hock;Leukemia Res.,2004
5. The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells;Lechmann;J. Exp. Med.,2001
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