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An improved water-soluble prodrug of propofol with high molecular utilization and rapid onset of action

  • Published:2019-01 Issue: Volume:127 Page:9-13
  • ISSN:0928-0987
  • Container-title:European Journal of Pharmaceutical Sciences
  • language:en
  • Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Zhang Weiyi,Yang Jun,Fan Jing,Wang Bin,Kang Yi,Liu Jin,Zhang Wensheng,Zhu Tao

Funder

National Major Scientific and Technological Special Project for “Significant New Drugs Development”

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference28 articles.

1. Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters;Altomare;Eur. J. Pharm. Sci.,2003

2. Infectious risks associated with the use of propofol;Bach;Acta Anaesthesiol. Scand.,1996

3. Propofol phosphate, a water-soluble propofol prodrug: in vivo evaluation;Banaszczyk;Anesth. Analg.,2002

4. Fospropofol: clinical pharmacology;Bengalorkar;J. Anaesthesiol. Clin. Pharmacol.,2011

5. Postoperative infections traced to contamination of an intravenous anesthetic, propofol;Bennett;N. Engl. J. Med.,1995
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