Optimised method to estimate octanol water distribution coefficient (logD) in a high throughput format
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference25 articles.
1. A high throughput dried DMSO LogD lipophilicity measurement based on 96-well shake-flask and atmospheric pressure photoionization mass spectrometry detection;Alelyunas;J. Chromat A.,2010
2. Setup and validation of shake-flask procedures for the determination of partition coefficients (logD) from low drug amounts;Andrés;Eur. J. Pharm. Sci.,2015
3. The binding of drugs to hepatocytes and its relationship to physicochemical properties;Austin;Drug Metab. Dispos.,2005
4. BDDCS applied to over 900 drugs;Benet;AAPS J.,2011
5. The measurement of partition coefficients;Dearden;Quant. Struct.-Act. Relat.,1988
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