Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach-Reference-Cited by-同舟云学术

Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach

Published:2018-01 Issue: Volume:112 Page:168-179
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Yamamoto Yumi,Välitalo Pyry A.,Wong Yin Cheong,Huntjens Dymphy R.,Proost Johannes H.,Vermeulen An,Krauwinkel Walter,Beukers Margot W.,Kokki Hannu,Kokki Merja,Danhof Meindert,van Hasselt Johan G.C.,de Lange Elizabeth C.M.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference77 articles.

1. Structure and function of the blood-brain barrier;Abbott;Neurobiol. Dis.,2010

2. The mega cisterna magna;Adam;J. Neurosurg.,1978

3. Stem cell-based human blood-brain barrier models for drug discovery and delivery;Aday;Trends Biotechnol.,2016

4. Cerebral blood flow and fMRI BOLD auditory language activation in temporal lobe epilepsy;Appel;Epilepsia,2012

5. Trial watch: phase II and phase III attrition rates 2011–2012;Arrowsmith;Nat. Rev. Drug Discov.,2013

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