Inhibition of human cytochrome P450 2A6 by 7-hydroxycoumarin analogues: Analysis of the structure-activity relationship and isoform selectivity-Reference-Cited by-同舟云学术

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Inhibition of human cytochrome P450 2A6 by 7-hydroxycoumarin analogues: Analysis of the structure-activity relationship and isoform selectivity

Published:2019-08 Issue: Volume:136 Page:104944
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Qi Xiaoyi,Dou Tongyi,Wang Zhongqiong,Wu Jianming,Yang Ling,Zeng Su,Deng Mingming,Lü Muhan,Liang Sicheng

Funder

National Natural Science Foundation

Science and Technology Support Project of Sichuan Province

Joint Fund of Luzhou City and Southwest Medical University

Fund of Southwest Medical University

Talent Introduction Startup Fund of Affiliated Hospital of Southwest Medical University

Open Program of Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference33 articles.

1. Quantitative structure-activity relationship and molecular docking studies of a series of quinazolinonyl analogues as inhibitors of gamma amino butyric acid aminotransferase;Abdulfatai;J. Adv. Res.,2017

2. Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration inmice: effects ofmethoxsalen, a CYP2A5/6 inhibitor;Alsharari;Nicotine Tob. Res.,2014

3. Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice;Bagdas;Neuropharmacology,2014

4. Deficient C-oxidation of nicotine;Benowitz;Clin. Pharmacol. Ther.,1995

5. Identification of the 4-position of 3-alkynyl and 3-heteroaromatic substituted pyridine methanamines as a key modification site eliciting increased potency and enhanced selectivity for cytochrome P-450 2A6 inhibition;Denton;J. Med. Chem.,2018

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1. Systematic Review of Naturally Derived Substances That Act as Inhibitors of the Nicotine Metabolizing Enzyme Cytochrome P450 2A6;International Journal of Molecular Sciences;2024-07-23

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3. Deciphering Structural Alterations Associated with Activity Reductions of Genetic Polymorphisms in Cytochrome P450 2A6 Using Molecular Dynamics Simulations;International Journal of Molecular Sciences;2021-09-19

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