Human lysosomal acid lipase/cholesteryl ester hydrolase and human gastric lipase: site-directed mutagenesis of Cys227 and Cys236 results in substrate-dependent reduction of enzymatic activity

Author:

Lohse P,Lohse P,Chahrokh-Zadeh S,Seidel D

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference46 articles.

1. Lysosomal acid lipase. In Lipases.;Fowler,1984

2. Acid lipase deficiency: Wolman disease and cholesteryl ester storage disease. In The Metabolic and Molecular Bases of Inherited Disease. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle , editors. McGraw-Hill, Inc., New York;Assmann,1995

3. Human lysosomal acid lipase/cholesteryl ester hydrolase. Purification and properties of the form secreted by fibroblasts in microcarrier culture;Sando;J. Biol. Chem.,1985

4. Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase;Anderson;J. Biol. Chem.,1991

5. Molecular cloning of a human gastric lipase and expression of the enzyme in yeast;Bodmer;Biochim. Bio-phys. Acta.,1987

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