Presenilin-1 L166P Mutant Human Pluripotent Stem Cell–Derived Neurons Exhibit Partial Loss of γ-Secretase Activity in Endogenous Amyloid-β Generation-Reference-Cited by-同舟云学术

Presenilin-1 L166P Mutant Human Pluripotent Stem Cell–Derived Neurons Exhibit Partial Loss of γ-Secretase Activity in Endogenous Amyloid-β Generation

Published:2012-06 Issue:6 Volume:180 Page:2404-2416
ISSN:0002-9440
Container-title:The American Journal of Pathology
language:en
Short-container-title:The American Journal of Pathology

Author:

Koch Philipp,Tamboli Irfan Y.,Mertens Jerome,Wunderlich Patrick,Ladewig Julia,Stüber Kathrin,Esselmann Hermann,Wiltfang Jens,Brüstle Oliver,Walter Jochen

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference43 articles.

1. Alzheimer's disease: genes, proteins, and therapy;Selkoe;Physiol Rev,2001

2. The cell biology of Alzheimer's disease: uncovering the secrets of secretases;Walter;Curr Opin Neurobiol,2001

3. BACE1 structure and function in health and Alzheimer's disease;Cole;Curr Alzheimer Res,2008

4. Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation;Page;J Biol Chem,2008

5. Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase;Czirr;J Biol Chem,2008

Cited by 99 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. γ-secretase facilitates retromer-mediated retrograde transport;2024-06-07

2. Human stem cell transplantation models of Alzheimer’s disease;Frontiers in Aging Neuroscience;2024-02-21

3. Quantitative comparison of presenilin protein expression reveals greater activity of PS2‐γ‐secretase;The FASEB Journal;2023-12-29

4. Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development;Cell Reports;2023-11

5. eMIND: Enabling automatic collection of protein variation impacts in Alzheimer’s disease from the literature;2023-09-12