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Spontaneous Insertion of a B2 Element in the Ptpn6 Gene Drives a Systemic Autoinflammatory Disease in Mice Resembling Neutrophilic Dermatosis in Humans

  • Published:2011-04 Issue:4 Volume:178 Page:1701-1714
  • ISSN:0002-9440
  • Container-title:The American Journal of Pathology
  • language:en
  • Short-container-title:The American Journal of Pathology

Author:

Nesterovitch Andrew B.,Szanto Sandor,Gonda Andrea,Bardos Tamas,Kis-Toth Katalin,Adarichev Vyacheslav A.,Olasz Katalin,Ghassemi-Najad Sheida,Hoffman Mark D.,Tharp Michael D.,Mikecz Katalin,Glant Tibor T.

Funder

J.O. Galante Endowment Chair at Rush University Medical Center

Grainger Foundation

Clark W. Finnerud MD Endowment Chair

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference80 articles.

1. Motheaten, an immunodeficient mutant of the mouse. I. Genetics and pathology;Green;J Hered,1975

2. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene;Shultz;Cell,1993

3. Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene;Tsui;Nat Genet,1993

4. The mouse mutant “motheaten” I. Development of lymphocyte populations;Sidman;J Immunol,1978

5. The mouse mutant “motheaten” II. Functional studies of the immune system;Sidman;J Immunol,1978

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