The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity

Author:

Kameyama Hirokazu,Uchimura Kenji,Yamashita Taro,Kuwabara Kaori,Mizuguchi Mineyuki,Hung Shang-Cheng,Okuhira Keiichiro,Masuda Tomohiro,Kosugi Tomoki,Ohgita Takashi,Saito Hiroyuki,Ando Yukio,Nishitsuji Kazuchika

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference84 articles.

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2. Heparan sulfate: growth control with a restricted sequence menu;Gallagher;J Clin Invest,2001

3. Order out of chaos: assembly of ligand binding sites in heparan sulfate;Esko;Annu Rev Biochem,2002

4. Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein;Noborn;Proc Natl Acad Sci U S A,2011

5. The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease;Snow;Am J Pathol,1988

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