Design and Synthesis of 6‐ O ‐Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid β Aggregation

Author:

Uchimura Kenji1,Nishitsuji Kazuchika2,Chiu Li‐Ting3,Ohgita Takashi4,Saito Hiroyuki4,Allain Fabrice1,Gannedi Veeranjaneyulu3,Wong Chi‐Huey35,Hung Shang‐Cheng36ORCID

Affiliation:

1. Univ. Lille, CNRS UMR 8576 – UGSF - Unité de Glycobiologie Structurale et Fonctionnelle 59000 Lille France

2. Department of Biochemistry Wakayama Medical University 811–1 Kimiidera Wakayama 641-8509 Japan

3. Genomics Research Center Academia Sinica, 128, Section 2 Academia Road Taipei 11529 Taiwan

4. Department of Biophysical Chemistry Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho Yamashina-ku Kyoto 607-8414 Japan

5. Department of Chemistry The Scripps Research Institute 10550 North Torrey Pines Road BCC 338 La Jolla CA 92037 USA

6. Department of Applied Science National Taitung University 369, Section 2 University Road Taitung 95092 Taiwan

Funder

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference90 articles.

1.  

2. Propagation of Protein Aggregation in Neurodegenerative Diseases

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4. National Down Syndrome Society Alzheimer's Disease and Down Syndrome Available at:https://www.ndss.org/resources/alzheimers. Accessed December 23 2020;

5. W. He D. Goodkind P. Kowal U. S. Census Bureau International Population Reports P95/16-1 An Aging World: 2015 U. S. Government Publishing Office Washington D. C. 2016. Available at:http://www.census.gov/content/dam/Census/library/publications/2016/demo/p95-16-1.pdf. Accessed December 23 2020.

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