Lysophosphatidic Acid Increases Proximal Tubule Cell Secretion of Profibrotic Cytokines PDGF-B and CTGF through LPA2- and Gαq-Mediated Rho and αvβ6 Integrin-Dependent Activation of TGF-β-Reference-Cited by-同舟云学术

Lysophosphatidic Acid Increases Proximal Tubule Cell Secretion of Profibrotic Cytokines PDGF-B and CTGF through LPA2- and Gαq-Mediated Rho and αvβ6 Integrin-Dependent Activation of TGF-β

Published:2012-10 Issue:4 Volume:181 Page:1236-1249
ISSN:0002-9440
Container-title:The American Journal of Pathology
language:en
Short-container-title:The American Journal of Pathology

Author:

Geng Hui,Lan Rongpei,Singha Prajjal K.,Gilchrist Annette,Weinreb Paul H.,Violette Shelia M.,Weinberg Joel M.,Saikumar Pothana,Venkatachalam Manjeri A.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference62 articles.

1. Transforming growth factor-beta in acute renal failure: receptor expression, effects on proliferation, cellularity, and vascularization after recovery from injury;Spurgeon;Am J Physiol Renal Physiol,2005

2. Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury;Nath;Am J Physiol Renal Physiol,2011

3. Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia;Geng;Am J Pathol,2009

4. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury;Yang;Nat Med,2010

5. Extracellular matrix-related genes in kidney after ischemic injury: potential role for TGF-beta in repair;Basile;Am J Physiol,1998

Cited by 87 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metabolic reprogramming in septic acute kidney injury: pathogenesis and therapeutic implications;Metabolism;2024-09

2. Effects of short‐ and long‐term use of propolis extracts on liver and kidney in rats;Food Science & Nutrition;2024-05-13

3. Drugs targeting CTGF in the treatment of pulmonary fibrosis;Journal of Cellular and Molecular Medicine;2024-05

4. Lineage tracing reveals transient phenotypic adaptation of tubular cells during acute kidney injury;iScience;2024-03

5. Transforming growth factor-β receptors: versatile mechanisms of ligand activation;Acta Pharmacologica Sinica;2024-02-13