Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis-Reference-Cited by-同舟云学术

Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis

Published:2006-08 Issue:2 Volume:355 Page:165-174
ISSN:0003-2697
Container-title:Analytical Biochemistry
language:en
Short-container-title:Analytical Biochemistry

Author:

Gadgil Himanshu S.,Bondarenko Pavel V.,Pipes Gary D.,Dillon Thomas M.,Banks Douglas,Abel Jeffrey,Kleemann Gerd R.,Treuheit Michael J.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference32 articles.

1. Antibody humanization: a case of the “Emperor’s New Clothes”?;Clark;Immunol. Today,2000

2. The solution conformations of the subclasses of human IgG deduced from sedimentation and small angle X-ray scattering studies;Gregory;Mol. Immunol.,1987

3. The influence of glycosylation on the thermal stability and effector function expression of human IgG1–Fc: properties of a series of truncated glycoforms;Mimura;Mol. Immunol.,2000

4. Human/Mouse chimeric monoclonal antibodies with human IgG1, IgG2, IgG3, and IgG4 constant domains: electron microscopic and hydrodynamic characterization;Phillips;Mol. Immunol.,1994

5. Crystal structure of a neutralizing human IgG against HIV-1: a template for vaccine design;Saphire;Science,2001

Cited by 106 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of tyrosine sulfation in the variable region of a bispecific antibody and its effect on stability and biological activity;mAbs;2023-09-24

2. A global view of the human post-translational modification landscape;Biochemical Journal;2023-08-23

3. Multiattribute Monitoring of Charge-Based Heterogeneity of Recombinant Monoclonal Antibodies Using 2D HIC-WCX-MS;Analytical Chemistry;2022-10-19

4. Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus;Immunity;2022-09

5. Characterization of disulfide bridges pattern of recombinant human interleukin 12 fusion protein p40 subunit and identification and quantification of cysteinylated free cysteine 252;Rapid Communications in Mass Spectrometry;2022-05-16