Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening

Author:

Wagle Neil,Xian Jun,Shishova Ekaterina Y.,Wei Jie,Glicksman Marcie A.,Cuny Gregory D.,Stein Ross L.,Cohen David E.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference24 articles.

1. START: A lipid-binding domain in StAR HD–ZIP and signalling proteins;Ponting;Trends Biochem. Sci.,1999

2. Structure of human phosphatidylcholine transfer protein in complex with its ligand;Roderick;Nat. Struct. Biol.,2002

3. Structure and function of phosphatidylcholine transfer protein (PC–TP)/StarD2;Kanno;Biochim. Biophys. Acta,2007

4. Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2;Scapa;FASEB J.,2008

5. Homozygous disruption of Pctp modulates atherosclerosis in apolipoprotein E deficient mice;Wang;J. Lipid Res.,2006

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