Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C

Author:

Hamman Mitchell A.,Thompson Gary A.,Hall Stephen D.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference35 articles.

1. The metabolism of ibuprofen;Mills;Xenobiotica,1973

2. Stereoselective metabolism of ibuprofen in humans. Administration of R-, S- and racemic ibuprofen;Rudy;J Pharmacol Exp Ther,1991

3. Enantioselective disposition of ibuprofen in elderly persons with and without renal impairment;Rudy;J Pharmacol Exp Ther,1995

4. A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal anti-inflammatory drugs;Leeman;Drugs Exp Clin Res,1993

5. Stereoselective disposition of ibuprofen in patients with renal dysfunction;Chen;J Pharmacol Exp Ther,1994

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