Verapamil-stimulated glutathione transport by the multidrug resistance-associated protein (MRP1) in leukaemia cells11Abbreviations: MRP1, multidrug resistance-associated protein; BSO, buthioninesulphoximine; MDR, multidrug resistance; MTT, (3,-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; BSP, sulphobromophthalein; GST, glutathione S-transferase; and CFTR, cystic fibrosis transmembrane conductance regulator.

Author:

Cullen Karen V.,Davey Ross A.,Davey Mary W.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

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2. Structural, mechanistic and clinical aspects of MRP1;Hipfner;Biochim Biophys Acta,1999

3. The P-glycoprotein efflux pump;Sharom;J Membr Biol,1997

4. Inhibitors of MRP1-mediated multidrug resistance;Norman;Drugs of the Future,1998

5. Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil;Tsuruo;Cancer Res,1981

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