A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death-Reference-Cited by-同舟云学术

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A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death

Published:2020-12-14 Issue:2 Volume:13 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Ceder Sophia¹^ORCID,Eriksson Sofi E¹^ORCID,Cheteh Emarndeena H¹^ORCID,Dawar Swati²^ORCID,Corrales Benitez Mariana²,Bykov Vladimir J N¹^ORCID,Fujihara Kenji M²³^ORCID,Grandin Mélodie⁴⁵^ORCID,Li Xiaodun⁶^ORCID,Ramm Susanne⁷^ORCID,Behrenbruch Corina³⁴,Simpson Kaylene J⁷^ORCID,Hollande Frédéric⁴⁵^ORCID,Abrahmsen Lars⁸,Clemons Nicholas J²³^ORCID,Wiman Klas G¹^ORCID

Affiliation:

1. Department of Oncology‐Pathology Karolinska Institutet Stockholm Sweden

2. Peter MacCallum Cancer Centre Melbourne Vic. Australia

3. Sir Peter MacCallum Department of Oncology The University of Melbourne Parkville Vic. Australia

4. Department of Clinical Pathology The University of Melbourne Melbourne Vic. Australia

5. Victorian Comprehensive Cancer Centre University of Melbourne Centre for Cancer Research Melbourne Vic. Australia

6. MRC Cancer Unit University of Cambridge Cambridge UK

7. Peter MacCallum Cancer Centre Victorian Centre for Functional Genomics Melbourne Vic. Australia

8. Aprea Therapeutics AB Solna Sweden

Funder

Vetenskapsrådet

Cancerfonden

Barncancerfonden

Radiumhemmets Forskningsfonder

Knut och Alice Wallenbergs Stiftelse

Karolinska Institutet

National Health and Medical Research Council

Department of Health and Human Services, State Government of Victoria

Medical Research Council

Australian Cancer Research Foundation

Cancer Research UK

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201910852

Reference77 articles.

1. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells

2. Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma

3. Prognostic value of TP53 gene mutations in myelodysplastic syndromes and acute myeloid leukemia treated with azacitidine

4. An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules

5. What is synergy?;Berenbaum MC;Pharmacol Rev,1989

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