SHR2554, an EZH2 inhibitor, in relapsed or refractory mature lymphoid neoplasms: a first-in-human, dose-escalation, dose-expansion, and clinical expansion phase 1 trial

Author:

Song Yuqin,Liu Yanyan,Li Zhi-Ming,Li Lanfang,Su Hang,Jin Zhengming,Zuo Xuelan,Wu Jianyuan,Zhou Hui,Li Kunyan,He Chuan,Zhou Jianfeng,Qi Junyuan,Hao Siguo,Cai Zhen,Li Yijing,Wang Weiwei,Zhang Xiaojing,Zou Jianjun,Zhu Jun

Publisher

Elsevier BV

Subject

Hematology

Reference26 articles.

1. Aberrations of EZH2 in cancer;Chase;Clin Cancer Res,2011

2. The Polycomb complex PRC2 and its mark in life;Margueron;Nature,2011

3. Overcoming immune checkpoint blockade resistance via EZH2 inhibition;Kim;Trends Immunol,2020

4. Immune modulatory functions of EZH2 in the tumor microenvironment: implications in cancer immunotherapy;Wang;Am J Clin Exp Urol,2019

5. EZH2 mutations are frequent and represent an early event in follicular lymphoma;Bödör;Blood,2013

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