1. On the rational development of a new drug: the example of the fluorinated pyrimidines;Heidelberger;Cancer Treat Rep,1981
2. Standing the test of time: targeting thymidylate biosynthesis in cancer therapy;Wilson;Nat Rev Clin Oncol,2014
3. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study;Jackman;Cancer Res,1991
4. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes;Shih;Cancer Res,1997
5. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat Rev Cancer,2003