5-HT6 receptor agonist EMD386088 impairs behavioral flexibility and working memory

Author:

Amodeo Dionisio A.,Peterson Sophie,Pahua Alma,Posadas Rebekah,Hernandez Armando,Hefner Emily,Qi David,Vega Jesus

Funder

National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Behavioral Neuroscience

Reference69 articles.

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2. AVN-322 is a safe orally bio-available potent and highly selective antagonist of 5-HT6R with demonstrated ability to improve impaired memory in animal models;Ivachtchenk;Curr. Alzheimer Res.,2017

3. 5-HT 6 receptors: a novel target for cognitive enhancement;Mitchell;Pharmacol. Ther.,2005

4. 5‐HT6 antagonists as potential treatment for cognitive dysfunction;Liu;Drug Dev. Res.,2009

5. 5-HT6 receptor memory and amnesia: behavioral pharmacology—learning and memory processes;Meneses;Int. Rev. Neurobiol.,2011

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