Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity

Author:

Bradley Todd,Trama Ashley,Tumba Nancy,Gray Elin,Lu Xiaozhi,Madani Navid,Jahanbakhsh Fatemeh,Eaton Amanda,Xia Shi-Mao,Parks Robert,Lloyd Krissey E.,Sutherland Laura L.,Scearce Richard M.,Bowman Cindy M.,Barnett Susan,Abdool-Karim Salim S.,Boyd Scott D.,Melillo Bruno,Smith Amos B.,Sodroski Joseph,Kepler Thomas B.,Alam S.Munir,Gao Feng,Bonsignori Mattia,Liao Hua-Xin,Moody M. Anthony,Montefiori David,Santra Sampa,Morris Lynn,Haynes Barton F.

Funder

Center for HIV/AIDS Vaccine Immunology-Immunogen Discovery

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference59 articles.

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2. Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies;Back;J. Virol.,1993

3. HIV entry and tropism: the chemokine receptor connection;Berger;AIDS,1997

4. Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41;Blish;PLoS Med.,2008

5. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors;Bonsignori;J. Virol.,2011

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