Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

Author:

Ozonoff Al,Schaenman Joanna,Jayavelu Naresh Doni,Milliren Carly E.,Calfee Carolyn S.,Cairns Charles B.,Kraft Monica,Baden Lindsey R.,Shaw Albert C.,Krammer Florian,van Bakel Harm,Esserman Denise A.,Liu Shanshan,Sesma Ana Fernandez,Simon Viviana,Hafler David A.,Montgomery Ruth R.,Kleinstein Steven H.,Levy Ofer,Bime Christian,Haddad Elias K.,Erle David J.,Pulendran Bali,Nadeau Kari C.,Davis Mark M.,Hough Catherine L.,Messer William B.,Higuita Nelson I. Agudelo,Metcalf Jordan P.,Atkinson Mark A.,Brakenridge Scott C.,Corry David,Kheradmand Farrah,Ehrlich Lauren I.R.,Melamed Esther,McComsey Grace A.,Sekaly Rafick,Diray-Arce Joann,Peters Bjoern,Augustine Alison D.,Reed Elaine F.,Altman Matthew C.,Becker Patrice M.,Rouphael Nadine,Ozonoff Al,Schaenman Joanna,Jayavelu Naresh Doni,Milliren Carly E.,Calfee Carolyn S.,Cairns Charles B.,Kraft Monica,Baden Lindsey R.,Shaw Albert C.,Krammer Florian,van Bakel Harm,Esserman Denise A.,Liu Shanshan,Sesma Ana Fernandez,Simon Viviana,Hafler David A.,Montgomery Ruth R.,Kleinstein Steven H.,Levy Ofer,Bime Chris,Haddad Elias K.,Erle David J.,Pulendran Bali,Nadeau Kari C.,Davis Mark M,Hough Catherine L.,Messer William B.,Higuita Nelson I. Agudelo,Metcalf Jordan P.,Atkinson Mark A.,Brakenridge Scott C.,Corry David,Kheradmand Farrah,Ehrlich Lauren I.R.,Melamed Esther,McComsey Grace A.,Sekaly Rafick,Diray-Arce Joann,Peters Bjoern,Augustine Alison D.,Reed Elaine F.,McEnaney Kerry,Barton Brenda,Lentucci Claudia,Saluvan Mehmet,Chang Ana C.,Hoch Annmarie,Albert Marisa,Shaheen Tanzia,Kho Alvin T.,Thomas Sanya,Chen Jing,Murphy Maimouna D.,Cooney Mitchell,Presnell Scott,Fragiadakis Gabriela K.,Patel Ravi,Guan Leying,Gygi Jeremy,Pawar Shrikant,Brito Anderson,Khalil Zain,Maguire Cole,Fourati Slim,Overton James A.,Vita Randi,Westendorf Kerstin,Salehi-Rad Ramin,Leligdowicz Aleksandra,Matthay Michael A.,Singer Jonathan P.,Kangelaris Kirsten N.,Hendrickson Carolyn M.,Krummel Matthew F.,Langelier Charles R.,Woodruff Prescott G.,Powell Debra L.,Kim James N.,Simmons Brent,Goonewardene I. Michael,Smith Cecilia M.,Martens Mark,Mosier Jarrod,Kimura Hiroki,Sherman Amy C.,Walsh Stephen R.,Issa Nicolas C.,Dela Cruz Charles,Farhadian Shelli,Iwasaki Akiko,Ko Albert I.,Chinthrajah Sharon,Ahuja Neera,Rogers Angela J.,Artandi Maja,Siegel Sarah A.R.,Lu Zhengchun,Drevets Douglas A.,Brown Brent R.,Anderson Matthew L.,Guirgis Faheem W.,Thyagarajan Rama V.,Rousseau Justin F.,Wylie Dennis,Busch Johanna,Gandhi Saurin,Triplett Todd A.,Yendewa George,Giddings Olivia,Anderson Evan J.,Mehta Aneesh K.,Sevransky Jonathan E.,Khor Bernard,Rahman Adeeb,Stadlbauer Daniel,Dutta Jayeeta,Xie Hui,Kim-Schulze Seunghee,Gonzalez-Reiche Ana Silvia,van de Guchte Adriana,Farrugia Keith,Khan Zenab,Maecker Holden T.,Elashoff David,Brook Jenny,Ramires-Sanchez Estefania,Llamas Megan,Rivera Adreanne,Perdomo Claudia,Ward Dawn C.,Magyar Clara E.,Fulcher Jennifer A.,Abe-Jones Yumiko,Asthana Saurabh,Beagle Alexander,Bhide Sharvari,Carrillo Sidney A.,Chak Suzanna,Fragiadakis Gabriela K.,Ghale Rajani,Gonzalez Ana,Jauregui Alejandra,Jones Norman,Lea Tasha,Lee Deanna,Lota Raphael,Milush Jeff,Nguyen Viet,Pierce Logan,Prasad Priya A.,Rao Arjun,Samad Bushra,Shaw Cole,Sigman Austin,Sinha Pratik,Ward Alyssa,Willmore Andrew,Zhan Jenny,Rashid Sadeed,Rodriguez Nicklaus,Tang Kevin,Altamirano Luz Torres,Betancourt Legna,Curiel Cindy,Sutter Nicole,Paz Maria Tercero,Tietje-Ulrich Gayelan,Leroux Carolyn,Connors Jennifer,Bernui Mariana,Kutzler Michel A.,Edwards Carolyn,Lee Edward,Lin Edward,Croen Brett,Semenza Nicholas C.,Rogowski Brandon,Melnyk Nataliya,Woloszczuk Kyra,Cusimano Gina,Bell Mathew R.,Furukawa Sara,McLin Renee,Marrero Pamela,Sheidy Julie,Tegos George P.,Nagle Crystal,Mege Nathan,Ulring Kristen,Seyfert-Margolis Vicki,Conway Michelle,Francisco Dave,Molzahn Allyson,Erickson Heidi,Wilson Connie Cathleen,Schunk Ron,Sierra Bianca,Hughes Trina,Smolen Kinga,Desjardins Michael,van Haren Simon,Mitre Xhoi,Cauley Jessica,Li Xiaofang,Tong Alexandra,Evans Bethany,Montesano Christina,Licona Jose Humberto,Krauss Jonathan,Chang Jun Bai Park,Izaguirre Natalie,Chaudhary Omkar,Coppi Andreas,Fournier John,Mohanty Subhasis,Muenker M. Catherine,Nelson Allison,Raddassi Khadir,Rainone Michael,Ruff William E.,Salahuddin Syim,Schulz Wade L.,Vijayakumar Pavithra,Wang Haowei,Wunder Jr. Elsio,Young H. Patrick,Zhao Yujiao,Saksena Miti,Altman Deena,Kojic Erna,Srivastava Komal,Eaker Lily Q.,Bermúdez-González Maria C.,Beach Katherine F.,Sominsky Levy A.,Azad Arman R.,Carreño Juan Manuel,Singh Gagandeep,Raskin Ariel,Tcheou Johnstone,Bielak Dominika,Kawabata Hisaaki,Mulder Lubbertus CF,Kleiner Giulio,Lee Alexandra S.,Do Evan Do,Fernandes Andrea,Manohar Monali,Hagan Thomas,Blish Catherine A.,Din Hena Naz,Roque Jonasel,Yang Samuel,Brunton Amanda,Sullivan Peter E.,Strnad Matthew,Lyski Zoe L.,Coulter Felicity J.,Booth J. Leland,Sinko Lauren A.,Moldawer Lyle L.,Borresen Brittany,Roth-Manning Brittney,Song Li-Zhen,Nelson Ebony,Lewis-Smith Megan,Smith Jacob,Tipan Pablo Guaman,Siles Nadia,Bazzi Sam,Geltman Janelle,Hurley Kerin,Gabriele Gio,Sieg Scott,Vaysman Tatyana,Bristow Laurel,Hussaini Laila,Hellmeister Kieffer,Samaha Hady,Cheng Andrew,Spainhour Christine,Scherer Erin M.,Johnson Brandi,Bechnak Amer,Ciric Caroline R.,Hewitt Lauren,Carter Erin,Mcnair Nina,Panganiban Bernadine,Huerta Christopher,Usher Jacob,Ribeiro Susan Pereira,Altman Matthew C.,Becker Patrice M.,Rouphael Nadine

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference37 articles.

1. Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans;Arunachalam;Science,2020

2. Immunophenotyping assessment in a COVID-19 cohort (IMPACC): a prospective longitudinal study;Sci Immunol,2021

3. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies;von Elm;Lancet,2007

4. World health organization. WHO R&D blueprint novel coronavirus COVID-19 therapeutic trial synopsis. 2020.https://www.who.int/blueprint/priority-diseases/key-action/COVID-19_Treatment_Trial_Design_Master_Protocol_synopsis_Final_18022020.pdf. Accessed 18 February 2020.

5. Centers for Disease Control and Prevention. Research use only 2019-novel coronavirus (2019-nCoV) real-time RT-PCR primers and probes. 2020, June 6. https://www.cdc.gov/coronavirus/2019-ncov/lab/rt-pcr-panel-primer-probes.html.

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