Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss-Reference-Cited by-同舟云学术

Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss

Published:2010-09 Issue:5 Volume:6 Page:378-385
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Mielke Michelle M.¹,Haughey Norman J.²,Bandaru Veera Venkata Ratnam²,Schech Steven¹,Carrick Richard¹,Carlson Michelle C.³⁴,Mori Susumu⁵⁶,Miller Michael I.⁷,Ceritoglu Can⁷,Brown Timothy⁷,Albert Marilyn²,Lyketsos Constantine G.¹

Affiliation:

1. Division of Geriatric Psychiatry and Neuropsychiatry, Department of PsychiatryJohns Hopkins University School of MedicineBaltimoreMDUSA

2. Department of NeurologyJohns Hopkins University School of MedicineBaltimoreMDUSA

3. Center on Aging and Health, Johns Hopkins University School of MedicineBaltimoreMDUSA

4. Department of Mental HealthJohns Hopkins University Bloomberg School of Public HealthBaltimoreMDUSA

5. Department of RadiologyJohns Hopkins University School of MedicineBaltimoreMDUSA

6. F.M. Kirby Center on Brain Imaging at the Kennedy Kreiger Institute, Johns Hopkins UniversityBaltimoreMDUSA

7. Center for Imaging Science, The Johns Hopkins UniversityBaltimoreMDUSA

Funder

National Institute on Aging

National Institute of Neurological Disorders and Stroke

GlaxoSmithKline

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Clinical Neurology,Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2010.03.014

Reference31 articles.

1. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

2. Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

3. Deregulation of sphingolipid metabolism in Alzheimer's disease

4. Astroglial expression of ceramide in Alzheimer's disease brains: A role during neuronal apoptosis

5. Exclusively targeting -secretase to lipid rafts by GPI-anchor addition up-regulates -site processing of the amyloid precursor protein

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