Exclusively targeting -secretase to lipid rafts by GPI-anchor addition up-regulates -site processing of the amyloid precursor protein
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference35 articles.
1. Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase
2. Purification and cloning of amyloid precursor protein β-secretase from human brain
3. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE
4. Aph-1, Pen-2, and Nicastrin with Presenilin Generate an Active γ-Secretase Complex
5. The Search for α-Secretase and its Potential as a Therapeutic Approach to Alzheimer's Disease
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