Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Author:

Kim Min12,Snowden Stuart134,Suvitaival Tommi2,Ali Ashfaq2,Merkler David J.5,Ahmad Tahmina1,Westwood Sarah6,Baird Alison6,Proitsi Petroula7,Nevado‐Holgado Alejo6,Hye Abdul2,Bos Isabelle8,Vos Stephanie8,Vandenberghe Rik9,Teunissen Charlotte10,Kate Mara10,Scheltens Philip11,Gabel Silvy912,Meersmans Karen912,Blin Olivier13,Richardson Jill14,De Roeck Ellen15,Sleegers Kristel1516,Bordet Régis17,Rami Lorena18,Kettunen Petronella192021,Tsolaki Magda22,Verhey Frans8,Sala Isabel23,Lléo Alberto23,Peyratout Gwendoline24,Tainta Mikel25,Johannsen Peter26,Freund‐Levi Yvonne2728,Frölich Lutz29,Dobricic Valerija30,Engelborghs Sebastiaan153031,Frisoni Giovanni B.32,Molinuevo José L.1833,Wallin Anders19,Popp Julius2434,Martinez‐Lage Pablo25,Bertram Lars35,Barkhof Frederik10,Ashton Nicholas219,Blennow Kaj1936,Zetterberg Henrik19363738,Streffer Johannes39,Visser Pieter J.810,Lovestone Simon6,Legido‐Quigley Cristina12

Affiliation:

1. Institute of Pharmaceutical ScienceKing's College LondonLondonUK

2. Steno Diabetes Center CopenhagenGentofteDenmark

3. Institute of Metabolic ScienceUniversity of CambridgeCambridgeUK

4. Department of BiochemistryUniversity of CambridgeCambridgeUK

5. Department of ChemistryUniversity of South FloridaTampaFLUSA

6. Department of PsychiatryUniversity of OxfordOxfordUK

7. Institute of PsychiatryPsychology and NeuroscienceMaurice Wohl Clinical Neuroscience InstituteKing's College LondonLondonUK

8. Alzheimer Centrum LimburgMaastricht UniversityMaastrichtThe Netherlands

9. University Hospital LeuvenLeuvenBelgium

10. Neurochemistry Laboratory and BiobankDepartment of Clinical ChemistryAmsterdam University Medical CentersAmsterdam NeuroscienceAmsterdamThe Netherlands

11. Department of NeurologyAlzheimer CenterAmsterdam University Medical CentersAmsterdamThe Netherlands

12. Laboratory for Cognitive NeurologyDepartment of NeurosciencesKU LeuvenLeuvenBelgium

13. Service de Pharmacologie Clinique et PharmacovigilanceInstitut de Neurosciences des SystèmesAix Marseille UniversityAPHMINSERMMarseilleFrance

14. Neurosciences Therapeutic AreaGlaxoSmithKline R&DStevenageUK

15. Institute Born‐BungeUniversity of AntwerpAntwerpBelgium

16. Neurodegenerative Brain Diseases GroupCenter for Molecular NeurologyVIBFlandersBelgium

17. University of LilleINSERMCHUDegenerative and Vascular Cognitive DisordersLilleLilleFrance

18. Alzheimer's Disease and Other Cognitive Disorders UnitHospital Clinic—IDIBAPSBarcelonaSpain

19. Institute of Neuroscience and PhysiologySahlgrenska AcademyUniversity of GothenburgGothenburgSweden

20. Memory Clinic at Department of NeuropsychiatrySahlgrenska University HospitalGothenburgSweden

21. Nuffield Department of Clinical NeurosciencesUniversity of OxfordWest WingJohn Radcliffe HospitalOxfordUK

22. First Department of NeurologyAHEPA University HospitalMakedoniaThessalonikiGreece

23. Memory UnitNeurology DepartmentHospital de la Santa Creu i Sant PauBarcelonaSpain

24. University Hospital of LausanneLausanneSwitzerland

25. CITA‐Alzheimer FoundationSan SebastianSpain

26. Danish Dementia Research CentreRigshospitaletCopenhagen University HospitalCopenhagenDenmark

27. Department of NeurobiologyCaring Sciences and Society (NVS)Division of Clinical GeriatricsKarolinska InstitutetStockholmSweden

28. Department of Geriatric MedicineKarolinska University Hospital HuddingeStockholmSweden

29. Department of Geriatric PsychiatryZentralinstitut für Seelische GesundheitUniversity of HeidelbergMannheimGermany

30. Lübeck Interdisciplinary Platform for Genome AnalyticsUniversity of LübeckGermany

31. Department of Neurology and Memory ClinicHospital Network Antwerp (ZNA) Middelheim and Hoge BeukenAntwerpBelgium

32. University of GenevaGenevaSwitzerland

33. Barcelona Beta Brain Research CenterPasqual Maragall FoundationBarcelonaSpain

34. Geriatric PsychiatryDepartment of Mental Health and PsychiatryGeneva University HospitalsGenevaSwitzerland

35. University of LübeckLübeckGermany

36. Clinical Neurochemistry LaboratorySahlgrenska University HospitalMölndalSweden

37. Department of Molecular NeuroscienceUCL Institute of NeurologyLondonUK

38. UK Dementia Research Institute at UCLLondonUK

39. Experimental MedicineJanssen Pharmaceutical CompaniesBeerseBelgium

Funder

Seventh Framework Programme

Fifth Framework Programme

National Institutes of Health

Novartis

Innovative Medicines Initiative

EFPIA

European Commission

Basque Government

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Clinical Neurology,Developmental Neuroscience,Health Policy,Epidemiology

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