A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression-Reference-Cited by-同舟云学术

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Published:2016-12-08 Issue:6 Volume:13 Page:663-673
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Carrasquillo Minerva M.¹,Allen Mariet¹,Burgess Jeremy D.¹,Wang Xue²,Strickland Samantha L.¹,Aryal Shivani¹,Siuda Joanna¹,Kachadoorian Michaela L.¹,Medway Christopher¹³,Younkin Curtis S.¹,Nair Asha⁴,Wang Chen⁴,Chanana Pritha⁴,Serie Daniel²,Nguyen Thuy¹,Lincoln Sarah¹,Malphrus Kimberly G.¹,Morgan Kevin³,Golde Todd E.⁵,Price Nathan D.⁶,White Charles C.⁷⁸⁹¹⁰,De Jager Philip L.⁷⁸⁹¹⁰¹¹,Bennett David A.¹²,Asmann Yan W.²,Crook Julia E.²,Petersen Ronald C.¹³,Graff‐Radford Neill R.¹⁴,Dickson Dennis W.¹,Younkin Steven G.¹,Ertekin‐Taner Nilüfer¹¹⁴

Affiliation:

1. Department of Neuroscience Mayo Clinic Florida Jacksonville FL USA

2. Department of Health Sciences Research Mayo Clinic Florida Jacksonville FL USA

3. Human Genetics Group University of Nottingham Nottingham UK

4. Department of Health Sciences Research Mayo Clinic Rochester MN USA

5. Department of Neuroscience University of Florida Gainesville FL USA

6. Institute for Systems Biology Seattle WA USA

7. Ann Romney Center for Neurologic Diseases Brigham and Women's Hospital Boston MA USA

8. Department of Neurology Brigham and Women's Hospital Boston MA USA

9. Department of Psychiatry Brigham and Women's Hospital Boston MA USA

10. Program in Medical and Population Genetics Broad Institute Cambridge MA USA

11. Department of Neurology Harvard Medical School Boston MA USA

12. Rush Alzheimer's Disease Center Rush University Medical Center Chicago IL USA

13. Department of Neurology Mayo Clinic Minnesota Rochester MN USA

14. Department of Neurology Mayo Clinic Florida Jacksonville FL USA

Funder

Alzheimer's Association

National Institute on Aging

National Institute of Neurological Disorders and Stroke

gs1:

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2016.10.005

Reference36 articles.

1. TREM2 Variants in Alzheimer's Disease

2. Variant ofTREM2Associated with the Risk of Alzheimer's Disease

3. TREM and TREM-like receptors in inflammation and disease

4. TREM2 and Risk of Alzheimer’s Disease — Friend or Foe?

5. TREM2 R47H Variant as a Risk Factor for Early-Onset Alzheimer's Disease

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