Metabolic network failures in Alzheimer's disease: A biochemical road map

Author:

Toledo Jon B.12,Arnold Matthias3,Kastenmüller Gabi34,Chang Rui5,Baillie Rebecca A.6,Han Xianlin7,Thambisetty Madhav8,Tenenbaum Jessica D.9,Suhre Karsten310,Thompson J. Will11,John‐Williams Lisa St.11,MahmoudianDehkordi Siamak12,Rotroff Daniel M.12,Jack John R.12,Motsinger‐Reif Alison12,Risacher Shannon L.1314,Blach Colette159,Lucas Joseph E.16,Massaro Tyler16,Louie Gregory1718,Zhu Hongjie1718,Dallmann Guido19,Klavins Kristaps19,Koal Therese19,Kim Sungeun1314,Nho Kwangsik1314,Shen Li1314,Casanova Ramon8,Varma Sudhir8,Legido‐Quigley Cristina20,Moseley M. Arthur11,Zhu Kuixi5,Henrion Marc Y.R.5,Lee Sven J.21,Harms Amy C.22,Demirkan Ayse21,Hankemeier Thomas2122,Duijn Cornelia M.2122,Trojanowski John Q.1,Shaw Leslie M.1,Saykin Andrew J.1314,Weiner Michael W.23,Doraiswamy P. Murali1718,Kaddurah‐Daouk Rima171824,

Affiliation:

1. Department of Pathology & Laboratory Medicine University of Pennsylvania Philadelphia PA USA

2. Department of Neurology Houston Methodist Hospital Houston TX USA

3. Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany

4. German Center for Diabetes Research (DZD) Neuherberg Germany

5. Department of Genetics and Genomic Science Icahn School of Medicine at Mount Sinai New York NY USA

6. Rosa & Co LLC San Carlos CA USA

7. Sanford Burnham Prebys Medical Discovery Institute Orlando FL USA

8. Clinical and Translational Neuroscience Unit, Laboratory of Behavioral Neuroscience, National Institute on Aging National Institutes of Health Baltimore MD USA

9. Department of Biostatistics and Bioinformatics Duke University Durham NC USA

10. Department of Physiology and Biophysics Weill Cornell Medical College Doha Qatar

11. Duke Proteomics and Metabolomics Shared Resource, Center for Genomic and Computational Biology Duke University Durham NC USA

12. Bioinformatics Research Center Department of Statistics North Carolina State University Raleigh NC USA

13. Department of Radiology and Imaging Sciences Indiana University School of Medicine Indianapolis IN USA

14. The Indiana Alzheimer Disease Center Indiana University School of Medicine Indianapolis IN USA

15. Duke Molecular Physiology Institute Duke University Durham NC USA

16. Institute for Genome Sciences and Policy Duke University Durham NC USA

17. Department of Psychiatry Duke University Durham NC USA

18. Duke Institute for Brain Sciences Duke University Durham NC USA

19. BIOCRATES Life Sciences AG Innsbruck Austria

20. IPS, Faculty of Life Sciences and Medicine King's College London London

21. Department of Epidemiology ErasmusMC Rotterdam The Netherlands

22. Analytical Biosciences, Leiden Academic Centre for Drug Research Leiden University Leiden Netherlands

23. Department of Radiology, Center for Imaging of Neurodegenerative Diseases San Francisco VA Medical Center/University of California San Francisco San Francisco CA USA

24. Department of Medicine Duke University Medical Center Durham NC USA

Funder

National Institute on Aging

U.S. National Library of Medicine

National Institute of Biomedical Imaging and Bioengineering

Alzheimer's Association

National Institutes of Health

U.S. Department of Defense

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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