Early striatal amyloid deposition distinguishes Down syndrome and autosomal dominant Alzheimer's disease from late‐onset amyloid deposition-Reference-Cited by-同舟云学术

Early striatal amyloid deposition distinguishes Down syndrome and autosomal dominant Alzheimer's disease from late‐onset amyloid deposition

Published:2018-02-22 Issue:6 Volume:14 Page:743-750
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Cohen Ann D.¹,McDade Eric²³,Christian Brad⁴,Price Julie⁵⁶,Mathis Chester⁵,Klunk William¹²,Handen Benjamin L.¹

Affiliation:

1. Department of PsychiatryUniversity of Pittsburgh School of MedicinePittsburghPAUSA

2. Department of NeurologyUniversity of Pittsburgh School of MedicinePittsburghPAUSA

3. Department of NeurologyWashington University School of MedicineSt. LouisMOUSA

4. Department of Medical PhysicsUniversity of Wisconsin–Madison School of MedicineMadisonWIUSA

5. Department of RadiologyUniversity of Pittsburgh School of MedicinePittsburghPAUSA

6. A. A. Martinos Center for Biomedical ImagingMassachusetts General HospitalCambridgeMAUSA

Funder

National Institutes of Health

Eli Lilly and Company

Roche

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.jalz.2018.01.002

Reference37 articles.

1. The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain

2. Sequence of Deposition of Heterogeneous Amyloid β-Peptides and APO E in Down Syndrome: Implications for Initial Events in Amyloid Plaque Formation

3. The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

4. Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer’s disease

5. Imaging brain amyloid in nondemented young adults with Down syndrome using Pittsburgh compound B

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