Elevated alkaline phosphatase velocity strongly predicts overall survival and the risk of bone metastases in castrate-resistant prostate cancer121Funding/support: This research was supported and funded through the Center for Prostate Disease Research (CPDR), the Uniformed Services University of the Health Sciences, the Intramural Research Program of the Clinical Research Center, and the National Cancer Institute, National Institutes of Health, Bethesda, MD, US.2Presentations: These data were presented at the 2012 Annual Meeting of the American Urological Association in Atlanta, GA.
Author:
Publisher
Elsevier BV
Subject
Urology,Oncology
Reference21 articles.
1. Serum alkaline phosphatase changes predict survival independent of PSA changes in men with castration-resistant prostate cancer and bone metastasis receiving chemotherapy;Sonpavde;Urol Oncol,2010
2. Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer;Cook;Clin Cancer Res,2006
3. Bone turnover markers as predictors of mortality risk in prostate cancer patients with bone metastases following treatment with zoledronic acid;Jung;Eur Urol,2011
4. Serial markers of bone turnover in men with metastatic prostate cancer treated with zoledronic acid for detection of bone metastases progression;Lein;Eur Urol,2007
5. Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: results of a phase 3, randomised, placebo-controlled trial;Smith;Lancet,2012
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