Current status ofN-,O-,S-heterocycles as potential alkaline phosphatase inhibitors: a medicinal chemistry overview-Reference-Cited by-同舟云学术

Current status ofN-,O-,S-heterocycles as potential alkaline phosphatase inhibitors: a medicinal chemistry overview

Published:2023 Issue:24 Volume:13 Page:16413-16452
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jassas Rabab S.¹,Naeem Nafeesa²^ORCID,Sadiq Amina³,Mehmood Rabia³,Alenazi Noof A.⁴,Al-Rooqi Munirah M.⁵,Mughal Ehsan Ullah²^ORCID,Alsantali Reem I.⁶,Ahmed Saleh A.⁵^ORCID

Affiliation:

1. Department of Chemistry, Jamoum University College, Umm Al-Qura University, Makkah 21955, Saudi Arabia

2. Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

3. Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan

4. Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia

5. Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, 21955 Makkah, Saudi Arabia

6. Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

Abstract

Heterocycles, powerful inhibitors of alkaline phosphatase (AP), are compounds that hinder an enzyme crucial for vital physiological functions including bone metabolism, cell growth, and differentiation.

Funder

Higher Education Commission, Pakistan

Umm Al-Qura University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA01888A

Reference174 articles.

1. Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery

2. Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase