Current status ofN-,O-,S-heterocycles as potential alkaline phosphatase inhibitors: a medicinal chemistry overview

Author:

Jassas Rabab S.1,Naeem Nafeesa2ORCID,Sadiq Amina3,Mehmood Rabia3,Alenazi Noof A.4,Al-Rooqi Munirah M.5,Mughal Ehsan Ullah2ORCID,Alsantali Reem I.6,Ahmed Saleh A.5ORCID

Affiliation:

1. Department of Chemistry, Jamoum University College, Umm Al-Qura University, Makkah 21955, Saudi Arabia

2. Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan

3. Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan

4. Department of Chemistry, College of Science and Humanities in Al-Kharj, Prince Sattam Bin Abdulaziz University, Al-kharj 11942, Saudi Arabia

5. Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, 21955 Makkah, Saudi Arabia

6. Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

Abstract

Heterocycles, powerful inhibitors of alkaline phosphatase (AP), are compounds that hinder an enzyme crucial for vital physiological functions including bone metabolism, cell growth, and differentiation.

Funder

Higher Education Commission, Pakistan

Umm Al-Qura University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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