The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs-Reference-Cited by-同舟云学术

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The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs

Published:2017-01 Issue:1 Volume:1863 Page:220-230
ISSN:0925-4439
Container-title:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Author:

Feng Chencheng,Zhang Yang,Yang Minghui,Lan Minghong,Liu Huan,Wang Jian,Zhou Yue,Huang Bo

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Molecular Biology,Molecular Medicine

Reference28 articles.

1. Senescence in human intervertebral discs;Roberts;Eur. Spine J.,2006

2. Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus;Gruber;Spine J.,2009

3. Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells;Dimozi;Eur. Cells Mater.,2015

4. Leg amputation accelerates senescence of rat lumbar intervertebral discs;Xing;Spine,2010

5. A role for TNFalpha in intervertebral disc degeneration: a non-recoverable catabolic shift;Purmessur;Biochem. Biophys. Res. Commun.,2013

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1. Causal relationship between basal metabolic rate and intervertebral disc degeneration: a Mendelian randomization study;European Spine Journal;2024-06-24

2. Mechanisms and therapeutic strategies for senescence-associated secretory phenotype in the intervertebral disc degeneration microenvironment;Journal of Orthopaedic Translation;2024-03

3. The sonic hedgehog pathway suppresses oxidative stress and senescence in nucleus pulposus cells to alleviate intervertebral disc degeneration via GPX4;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-02

4. Emerging role and therapeutic implications of p53 in intervertebral disc degeneration;Cell Death Discovery;2023-12-01

5. Senescence-associated alterations in the extracellular matrix: deciphering their role in the regulation of cellular function;American Journal of Physiology-Cell Physiology;2023-09-01

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