The sonic hedgehog pathway suppresses oxidative stress and senescence in nucleus pulposus cells to alleviate intervertebral disc degeneration via GPX4-Reference-Cited by-同舟云学术

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The sonic hedgehog pathway suppresses oxidative stress and senescence in nucleus pulposus cells to alleviate intervertebral disc degeneration via GPX4

Published:2024-02 Issue:2 Volume:1870 Page:166961
ISSN:0925-4439
Container-title:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Author:

Zhuang Yong,Liu Libangxi,Liu Miao,Fu Jiawei,Ai Xuezheng,Long Dan,Leng Xue,Zhang Yang,Gong Xunren,Shang Xianwen,Li Changqing,Huang Bo,Zhou Yue,Ning Xu,Dong Shiwu,Feng Chencheng

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Elsevier BV

Subject

Molecular Biology,Molecular Medicine

Reference44 articles.

1. Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017;Jin;Ann. Rheum. Dis.,2020

2. Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study;Livshits;Ann. Rheum. Dis.,2011

3. p16(Ink4a) deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence;Novais;Matrix Biol.,2019

4. Cartilage intermediate layer protein affects the progression of intervertebral disc degeneration by regulating the extracellular microenvironment (Review);Liu;Int. J. Mol. Med.,2020

5. Senescence of nucleus pulposus chondrocytes in human intervertebral discs;Kim;Asian Spine J.,2008

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