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Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts

  • Published:2014-04 Issue:1 Volume:323 Page:189-197
  • ISSN:0014-4827
  • Container-title:Experimental Cell Research
  • language:en
  • Short-container-title:Experimental Cell Research

Author:

Mao Shuai,Wang Yanting,Zhang Minzhou,Hinek Aleksander

Funder

Canadian Institute of Health Research

Heart and Stroke Foundation of Ontario

Oversea Study Program of Guangzhou Elite Project

Publisher

Elsevier BV

Subject

Cell Biology

Reference47 articles.

1. Safety and efficacy of an injectable extracellular matrix hydrogel for treating myocardial infarction;Sonya;Sci. Transl. Med.,2013

2. Getting to the heart of cardiac remodeling; how collagen subtypes may contribute to phenotype;Collier;J. Mol. Cell. Cardiol.,2012

3. Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner;Bunda;Am. J. Pathol.,2007

4. Tanshinone IIA: a promising natural cardio-protective agent;Shang;Evid.-Based Complement. Altern. Med.,2012

5. Concentration-dependent effects of the soy phytoestrogen genistein on the proteome of cultured cardiomyocytes;Sun;J. Proteomics,2012
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