Assay and single dose pharmacokinetics of a novel systemic acyl coenzyme A cholesterol O-acyltransferase inhibitor, RP 73163, in rat plasma using automated solid-phase extraction with high-performance liquid chromatography-Reference-Cited by-同舟云学术

Assay and single dose pharmacokinetics of a novel systemic acyl coenzyme A cholesterol O-acyltransferase inhibitor, RP 73163, in rat plasma using automated solid-phase extraction with high-performance liquid chromatography

Published:1994-11 Issue:1 Volume:661 Page:119-131
ISSN:0378-4347
Container-title:Journal of Chromatography B: Biomedical Sciences and Applications
language:en
Short-container-title:Journal of Chromatography B: Biomedical Sciences and Applications

Author:

Jones Graham D.,Hoff Trudy A.,Gunraj Paul E.,Facchini Vincenzo,Chauhan Pravin B.

Publisher

Elsevier BV

Subject

General Chemistry

Reference11 articles.

1. Acyl-CoA: cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT

2. RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT)

3. Esterification of cholesterol in human small intestine: the importance of acyl-CoA:cholesterol acyltransferase

4. Role of acyl CoA:cholesterol acyltransferase in cholesterol absorption and its inhibition by 57-118 in the rabbit.

5. Cholesterol absorption and transport in thoracic duct lymph lipoproteins of nonhuman primates. Effect of dietary cholesterol level

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1. Acyl coenzyme A:cholesterol acyltransferase inhibitors as hypolipidemic and antiatherosclerotic drugs;Methods and Findings in Experimental and Clinical Pharmacology;2004

2. Evaluation of an on-line solid-phase extraction method for determination of almokalant, an antiarrhythmic drug, by liquid chromatography;Journal of Chromatography B: Biomedical Sciences and Applications;1997-02

3. Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol;Biochemical Pharmacology;1996-10