RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT)-Reference-Cited by-同舟云学术

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RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT)

Published:1992-01 Issue:5 Volume:2 Page:375-380
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ashton M.J.,Bridge A.W.,Bush R.C.,Dron D.I.,Harris N.V.,Jones G.D.,Lythgoe D.J.,Riddell D.,Smith C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference8 articles.

1. Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.

2. Therapeutic potential of ACAT inhibitors as lipid lowering and anti-atherosclerotic agents

3. Coffee, E.C.J. Eur. Pat. 391796 (10 October 1990)

4. Billheimer, J.T.; Gillies, P.J.; Wexler, R.R.; Higley, C.A.; Maduskuie, T.P.; Eur. Pat. 372445 (13 June 1990)

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1. Targeting Sterol O-Acyltransferase/Acyl-CoA:Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential;Journal of Medicinal Chemistry;2022-12-06

2. Biocatalytical Asymmetric Sulfoxidation by Identifying Cytochrome P450 fromParvibaculum LavamentivoransDS‐1;ChemCatChem;2018-11-07

3. Synthesis and Biological Profiles of 4,5-, 1,5-, and 1,2-Diaryl-1 H -imidazoles;Vicinal Diaryl Substituted Heterocycles;2018

4. Synthesis of enyne and aryl vinyl sulfoxides: functionalization via Pummerer rearrangement;Molecular Diversity;2015-08-01

5. ACAT Inhibitors: The Search for Novel Cholesterol Lowering Agents;Mini-Reviews in Medicinal Chemistry;2013-05-01

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