Comparison of Phase I-II designs with parametric or semi-parametric models using two different risk-benefit trade-off criteria

Author:

Chapple Andrew G.,Thall Peter F.

Funder

NCI

Publisher

Elsevier BV

Subject

Pharmacology (medical),General Medicine

Reference22 articles.

1. Effective sample size for computing prior hyperparameters in Bayesian phase I-II dose-finding;Thall;Clin Trials J.,2014

2. A Bayesian phase I/II trial design for immunotherapy;Liu;J. Am. Stat. Assoc.,2018

3. Optimizing natural killer cell doses for heterogeneous cancer patients on the basis of multiple event times;Lee;J R Stat Soc Ser C Appl Stat.,2019

4. A strategy for dose finding and safety monitoring based on efficacy and adverse outcomes in phase I/II clinical trials;Thall;Biometrics.,1998

5. Bayesian approach to jointly modeling toxicity and biomarker expression in a phase I/II dose-finding trial;Bekele;Biometrics.,2005

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