Human Rotator Cuff Tears Reveal an Age-Dependent Increase in Markers of Cellular Senescence and Selective Removal of Senescent Cells With Dasatinib + Quercetin Increases Genetic Expression of COL1A1 In Vitro-Reference-Cited by-同舟云学术

Human Rotator Cuff Tears Reveal an Age-Dependent Increase in Markers of Cellular Senescence and Selective Removal of Senescent Cells With Dasatinib + Quercetin Increases Genetic Expression of COL1A1 In Vitro

Published:2024-01 Issue:1 Volume:40 Page:34-44
ISSN:0749-8063
Container-title:Arthroscopy: The Journal of Arthroscopic & Related Surgery
language:en
Short-container-title:Arthroscopy: The Journal of Arthroscopic & Related Surgery

Author:

Hawthorne Benjamin C.^ORCID,Wellington Ian J.^ORCID,Sabitsky Joshua T.^ORCID,Murphy Kyle V.,Karsmarski Owen P.,Thomas Rohin O.^ORCID,LeVasseur Matthew R.,Mancini Michael R.^ORCID,Trudeau Maxwell T.^ORCID,Gulati Sagar,McCarthy Mary Beth R.,Cote Mark P.,Xu Ming^ORCID,Mazzocca Augustus D.

Funder

Arthroscopy Association of North America

University of Connecticut

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine

Reference45 articles.

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2. Full-thickness rotator cuff tear prevalence and correlation with function and co-morbidities in patients sixty-five years and older;Fehringer;J Shoulder Elbow Surg,2008

3. Abnormal findings on magnetic resonance images of asymptomatic shoulders;Sher;J Bone Joint Surg Am,1995

4. Age-related prevalence of rotator cuff tears in asymptomatic shoulders;Tempelhof;J Shoulder Elbow Surg,1999

5. Correlation of age, acromial morphology, and rotator cuff tear pathology diagnosed by ultrasound in asymptomatic patients;Worland;J South Orthop Assoc,2003

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1. Cellular senescence impairs tendon extracellular matrix remodeling in response to mechanical unloading;Aging Cell;2024-07-22

2. Role of oxidative stress in the concurrent development of osteoporosis and tendinopathy: Emerging challenges and prospects for treatment modalities;Journal of Cellular and Molecular Medicine;2024-07

3. Biologic Adjuvants to Rotator Cuff Repairs Induce Anti-inflammatory Macrophage 2 Polarization and Reduce Inflammatory Macrophage 1 Polarization In Vitro;Arthroscopy: The Journal of Arthroscopic & Related Surgery;2024-05

4. Editorial Commentary: Dasatinib With Quercetin Shows Promise in Decreasing Age-Related Senescence in the Rotator Cuff Tendon—Can It Work Elsewhere?;Arthroscopy: The Journal of Arthroscopic & Related Surgery;2024-01

5. Cellular Senescence Impairs Tendon Extracellular Matrix Remodeling in Response to Mechanical Unloading;2023-12-23