Electron Density Guided Fragment-Based Drug Design—A Lead Generation Example

Author:

Abad Marta C.,Gibbs Alan C.,Zhang Xuqing

Publisher

Elsevier

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Residues in the fructose-binding pocket are required for ketohexokinase-A activity;Journal of Biological Chemistry;2024-08

2. Therapeutic Approaches for Nonalcoholic Steatohepatitis ( NASH );Burger's Medicinal Chemistry and Drug Discovery;2021-04-28

3. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK);Journal of Medicinal Chemistry;2017-09-11

4. Fragment-Based Drug Design: Strategic Advances and Lessons Learned;Comprehensive Medicinal Chemistry III;2017

5. Structural insights into the novel inhibition mechanism ofTrypanosoma cruzispermidine synthase;Acta Crystallographica Section D Biological Crystallography;2015-08-25

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